A unattractive female who is always seen with another female who is marginally more attractive. It is usually impossible to score with the hotter female without the duff receiving her fair share of the action.
Damn! I so wanna tap that chick.. but goddamn, she always has that duff Nicole hanging off her. Look at that fat mess!
viết bởi Steve0 20 Tháng tám, 2004
An abbreviation for 'Designated Ugly Fat Friend'. Often in many large groups of women (usually adolecents) there will be a D.U.F.F. as a means to look better by comparison.
I only hang out with her becuase I need a D.U.F.F., otherwise, she'd be, so, history.
viết bởi B.a.m 20 Tháng mười hai, 2005